• Tgen X Dell Technologies. Transforming Genomics

    Setting the pace of progress.

    • Company: TGen
    • Industry: Genomics Research Institute
    • Headquarters: Phoenix, Arizona

    Speed is imperative in the fight against rare diseases. Families need answers. People need treatment. For Translational Genomics Research Institute (TGen) and its Center for Rare Childhood Disorders, the Phoenix-based research and treatment center, shortening the "diagnostic odyssey" is only the beginning.

    For when life depends on data.

    TGen's precision medicine explorations bring better treatments to more patients. They take discoveries in the lab and translate them into treatment quickly and effectively. To do this requires being able to manipulate massive quantities of data — moving it to where it needs to be, managing it securely and processing it intelligently. How much data? Well, if you were type it all out, you'd need a stack of papers 300' tall. The analytical challenge of working with a data set of that size requires intelligent systems that can incorporate AI and machine learning. By automating baseline data interrogation, humans are free to focus on the finer points of what it all means. TGen's partnership with Dell Technologies to handle all these complexities results in better outcomes for researchers and patients alike.

    Precision medicine. Personalized care.

    What do we do with a piece of code 3 billion letters long? When it comes to rare diseases, we know that no two people are the same. Teams are now deploying technologies and methodologies that can treat the individual needs of each patient. In the case of neuroblastoma, when at one point two out of every three patients used to pass away from the disease, progress in this regard is imperative. The protocols and therapies that existed were not going to cut it. But for groups like TGen, being able to mine data from cases, coupled with a deep understanding of genomics helps create personalized, targeted treatment that's far superior than traditional methods, and they rely on Dell Technologies to help them find solutions to problems that haven't even been defined yet.

    “Our partnership with Dell Technologies has been a cornerstone to a lot of work that we've done, and has enabled TGen to stay ahead of the pack, and be a leader in precision medicine.”


    Mapping one human genome.

    According to Dr. Jeffrey Trent, TGen’s president and research director, if one were to type 60 words a minute, eight hours a day, it would take 50 years to record one human genome, creating a stack of paper as high as the Statue of Liberty — and a single misspelling could cause a disease. Dr. Trent credits TGen, Dell and EMC for forming an IT infrastructure that now allows scientists and clinicians to receive this critical information faster than ever thought possible.

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